Aqueous and Alcoholic Extracts of Triphala and Their Active Compounds Chebulagic Acid and Chebulinic Acid Prevented Epithelial to Mesenchymal Transition in Retinal Pigment Epithelial Cells, by Inhibiting SMAD-3 Phosphorylation

Epithelial to Mesenchymal Transition (EMT) of the retinal pigment epithelium is involved in the pathogenesis of proliferative vitreoretinopathy (PVR) that often leads to retinal detachment. In this study, Triphala, an ayurvedic formulation and two of its active ingredients, namely chebulagic acid an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sivasankar, Shanmuganathan, Lavanya, Ramu, Brindha, Pemaiah, Angayarkanni, Narayanasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368423/
https://www.ncbi.nlm.nih.gov/pubmed/25793924
http://dx.doi.org/10.1371/journal.pone.0120512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368423/
https://www.ncbi.nlm.nih.gov/pubmed/25793924
http://dx.doi.org/10.1371/journal.pone.0120512

Ejemplares similares