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Multi-Functional Regulation of 4E-BP Gene Expression by the Ccr4-Not Complex

The mechanistic target of rapamycin (mTOR) signaling pathway is highly conserved from yeast to humans. It senses various environmental cues to regulate cellular growth and homeostasis. Deregulation of the pathway has been implicated in many pathological conditions including cancer. Phosphorylation c...

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Detalles Bibliográficos
Autores principales: Okada, Hirokazu, Schittenhelm, Ralf B., Straessle, Anna, Hafen, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368434/
https://www.ncbi.nlm.nih.gov/pubmed/25793896
http://dx.doi.org/10.1371/journal.pone.0113902