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Multi-Functional Regulation of 4E-BP Gene Expression by the Ccr4-Not Complex
The mechanistic target of rapamycin (mTOR) signaling pathway is highly conserved from yeast to humans. It senses various environmental cues to regulate cellular growth and homeostasis. Deregulation of the pathway has been implicated in many pathological conditions including cancer. Phosphorylation c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368434/ https://www.ncbi.nlm.nih.gov/pubmed/25793896 http://dx.doi.org/10.1371/journal.pone.0113902 |