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Human Tyr-tRNA synthetase is a potent PARP-1 activating effector target for resveratrol
Resveratrol (RSV) is reported to extend life span(1,2) and provide cardio-neuro-protective(3), anti-diabetic(4), and anti-cancer effects(3,5) by initiating a stress response(2) that induces survival genes. Because human tyrosyl tRNA synthetase (TyrRS) translocates to the nucleus under stress conditi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368482/ https://www.ncbi.nlm.nih.gov/pubmed/25533949 http://dx.doi.org/10.1038/nature14028 |