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Asymmetric Genome Organization in an RNA Virus Revealed via Graph-Theoretical Analysis of Tomographic Data

Cryo-electron microscopy permits 3-D structures of viral pathogens to be determined in remarkable detail. In particular, the protein containers encapsulating viral genomes have been determined to high resolution using symmetry averaging techniques that exploit the icosahedral architecture seen in ma...

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Detalles Bibliográficos
Autores principales: Geraets, James A., Dykeman, Eric C., Stockley, Peter G., Ranson, Neil A., Twarock, Reidun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368512/
https://www.ncbi.nlm.nih.gov/pubmed/25793998
http://dx.doi.org/10.1371/journal.pcbi.1004146