Cargando…

Asymmetric Genome Organization in an RNA Virus Revealed via Graph-Theoretical Analysis of Tomographic Data

Cryo-electron microscopy permits 3-D structures of viral pathogens to be determined in remarkable detail. In particular, the protein containers encapsulating viral genomes have been determined to high resolution using symmetry averaging techniques that exploit the icosahedral architecture seen in ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geraets, James A., Dykeman, Eric C., Stockley, Peter G., Ranson, Neil A., Twarock, Reidun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368512/ https://www.ncbi.nlm.nih.gov/pubmed/25793998 http://dx.doi.org/10.1371/journal.pcbi.1004146

Ejemplares similares

A modelling paradigm for RNA virus assembly
por: Twarock, Reidun, et al.
Publicado: (2018)

RNA Virus Evolution via a Quasispecies-Based Model Reveals a Drug Target with a High Barrier to Resistance
por: Bingham, Richard J., et al.
Publicado: (2017)

The impact of local assembly rules on RNA packaging in a T = 1 satellite plant virus
por: Hill, Sam R., et al.
Publicado: (2021)

Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism
por: Stockley, Peter G., et al.
Publicado: (2013)

An Intracellular Model of Hepatitis B Viral Infection: An In Silico Platform for Comparing Therapeutic Strategies
por: Fatehi, Farzad, et al.
Publicado: (2020)

On the subgroup structure of the hyperoctahedral group in six dimensions
por: Zappa, Emilio, et al.
Publicado: (2014)

Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts
por: Chandler-Bostock, Rebecca, et al.
Publicado: (2020)

Direct Evidence for Packaging Signal-Mediated Assembly of Bacteriophage MS2
por: Rolfsson, Óttar, et al.
Publicado: (2016)

The HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly
por: Patel, Nikesh, et al.
Publicado: (2017)

Comparing antiviral strategies against COVID-19 via multiscale within-host modelling
por: Fatehi, F., et al.
Publicado: (2021)

Bacteriophage MS2 genomic RNA encodes an assembly instruction manual for its capsid
por: Stockley, Peter G., et al.
Publicado: (2016)

Percolation Theory Reveals Biophysical Properties of Virus-like Particles
por: Brunk, Nicholas E., et al.
Publicado: (2021)

Hamiltonian path analysis of viral genomes
por: Twarock, Reidun, et al.
Publicado: (2018)

Genomic RNA folding mediates assembly of human parechovirus
por: Shakeel, Shabih, et al.
Publicado: (2017)

Erratum: Genomic RNA folding mediates assembly of human parechovirus
por: Shakeel, Shabih, et al.
Publicado: (2017)

In vitro functional analysis of gRNA sites regulating assembly of hepatitis B virus
por: Patel, Nikesh, et al.
Publicado: (2021)

Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging
por: Stewart, H., et al.
Publicado: (2016)

An age-structured model of hepatitis B viral infection highlights the potential of different therapeutic strategies
por: Fatehi, Farzad, et al.
Publicado: (2022)

Rewriting nature’s assembly manual for a ssRNA virus
por: Patel, Nikesh, et al.
Publicado: (2017)

The Asymmetric Structure of an Icosahedral Virus Bound to Its Receptor Suggests a Mechanism for Genome Release
por: Dent, Kyle C., et al.
Publicado: (2013)

A30 Recombination & evolution in two viral families: effective steps or a random walk?
por: Bingham, R., et al.
Publicado: (2017)

Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus
por: Bakker, Saskia E., et al.
Publicado: (2012)

Therapeutic interfering particles exploiting viral replication and assembly mechanisms show promising performance: a modelling study
por: Fatehi, Farzad, et al.
Publicado: (2021)

A coarse-grained model of the expansion of the human rhinovirus 2 capsid reveals insights in genome release
por: Indelicato, Giuliana, et al.
Publicado: (2019)

Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands
por: Patel, Nikesh, et al.
Publicado: (2022)

Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation
por: Abulwerdi, Fardokht, et al.
Publicado: (2022)

Structural puzzles in virology solved with an overarching icosahedral design principle
por: Twarock, Reidun, et al.
Publicado: (2019)

Programmable polymorphism of a virus-like particle
por: Biela, Artur P., et al.
Publicado: (2022)

Limits of Structural Plasticity in a Picornavirus Capsid Revealed by a Massively Expanded Equine Rhinitis A Virus Particle
por: Bakker, Saskia E., et al.
Publicado: (2014)

A proposed simulation method for directed self-assembly of nanographene
por: Geraets, J A, et al.
Publicado: (2017)

Surface stresses in complex viral capsids and non-quasi-equivalent viral architectures
por: Indelicato, Giuliana, et al.
Publicado: (2020)

Mechanical and Assembly Units of Viral Capsids Identified via Quasi-Rigid Domain Decomposition
por: Polles, Guido, et al.
Publicado: (2013)

Graph-theoretical analysis for energy landscape reveals the organization of state transitions in the resting-state human cerebral cortex
por: Kang, Jiyoung, et al.
Publicado: (2019)

Dynamic network approach for the modelling of genomic sub-complexes in multi-segmented viruses
por: AlShaikhahmed, Kinda, et al.
Publicado: (2018)

Novel base triples in RNA structures revealed by graph theoretical searching methods
por: Firdaus-Raih, Mohd, et al.
Publicado: (2011)

Graph Theoretical Analysis Reveals: Women’s Brains Are Better Connected than Men’s
por: Szalkai, Balázs, et al.
Publicado: (2015)

Graph Theoretical Approaches in Brain Networks
por: De Vico Fallani, Fabrizio, et al.
Publicado: (2012)

A Graph Theoretical Approach to Study the Organization of the Cortical Networks during Different Mathematical Tasks
por: Klados, Manousos A., et al.
Publicado: (2013)

EEG characteristic analysis of coach bus drivers based on brain connectivity as revealed via a graph theoretical network
por: Wang, Fuwang, et al.
Publicado: (2018)

Assessment of Keratoconus Risk in Very Asymmetric Ectasia Using Corneal Tomographic and Biomechanical Parameters
por: Zhang, Xiaoyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5pjt9ohu1ef2umqfukevtmelah