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Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4(+) T-Lymphocytes

Bodily secretions, including breast milk and semen, contain factors that modulate HIV-1 infection. Since anal intercourse caries one of the highest risks for HIV-1 transmission, our aim was to determine whether colorectal mucus (CM) also contains factors interfering with HIV-1 infection and replicat...

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Detalles Bibliográficos
Autores principales: Stax, Martijn J., Mouser, Emily E. I. M., van Montfort, Thijs, Sanders, Rogier W., de Vries, Henry J. C., Dekker, Henk L., Herrera, Carolina, Speijer, Dave, Pollakis, Georgios, Paxton, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368515/
https://www.ncbi.nlm.nih.gov/pubmed/25793526
http://dx.doi.org/10.1371/journal.pone.0122020