An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging

Acute myeloid leukemia (AML) is a clinically and molecularly heterogeneous disease with poor outcome. Adequate model systems are required for preclinical studies to improve understanding of AML biology and to develop novel, rational treatment approaches. Xenografts in immunodeficient mice allow perf...

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Detalles Bibliográficos
Autores principales: Vick, Binje, Rothenberg, Maja, Sandhöfer, Nadine, Carlet, Michela, Finkenzeller, Cornelia, Krupka, Christina, Grunert, Michaela, Trumpp, Andreas, Corbacioglu, Selim, Ebinger, Martin, André, Maya C., Hiddemann, Wolfgang, Schneider, Stephanie, Subklewe, Marion, Metzeler, Klaus H., Spiekermann, Karsten, Jeremias, Irmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368518/
https://www.ncbi.nlm.nih.gov/pubmed/25793878
http://dx.doi.org/10.1371/journal.pone.0120925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368518/
https://www.ncbi.nlm.nih.gov/pubmed/25793878
http://dx.doi.org/10.1371/journal.pone.0120925

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