Optimization and Validation of High-Performance Chromatographic Condition for Simultaneous Determination of Adapalene and Benzoyl Peroxide by Response Surface Methodology

The aim of this study was to develop a simple and reliable high-performance chromatographic (HPLC) method for simultaneous analysis of adapalene and benzoyl peroxide in pharmaceutical formulation by response surface methodology (RSM). An optimized mobile phase composed of acetonitrile, tetrahydrofur...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Cheng, Tsai, Pi-Ju, Huang, Yaw-Bin, Wu, Pao-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368549/
https://www.ncbi.nlm.nih.gov/pubmed/25793581
http://dx.doi.org/10.1371/journal.pone.0120171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368549/
https://www.ncbi.nlm.nih.gov/pubmed/25793581
http://dx.doi.org/10.1371/journal.pone.0120171

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