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Optimization and Validation of High-Performance Chromatographic Condition for Simultaneous Determination of Adapalene and Benzoyl Peroxide by Response Surface Methodology

The aim of this study was to develop a simple and reliable high-performance chromatographic (HPLC) method for simultaneous analysis of adapalene and benzoyl peroxide in pharmaceutical formulation by response surface methodology (RSM). An optimized mobile phase composed of acetonitrile, tetrahydrofur...

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Detalles Bibliográficos
Autores principales:	Chen, Yi-Cheng, Tsai, Pi-Ju, Huang, Yaw-Bin, Wu, Pao-Chu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368549/ https://www.ncbi.nlm.nih.gov/pubmed/25793581 http://dx.doi.org/10.1371/journal.pone.0120171

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