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Standard Sub-Thermoneutral Caging Temperature Influences Radiosensitivity of Hematopoietic Stem and Progenitor Cells

The production of new blood cells relies on a hierarchical network of hematopoietic stem and progenitor cells (HSPCs). To maintain lifelong hematopoiesis, HSPCs must be protected from ionizing radiation or other cytotoxic agents. For many years, murine models have been a valuable source of informati...

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Detalles Bibliográficos
Autores principales: Povinelli, Benjamin J., Kokolus, Kathleen M., Eng, Jason W.-L., Dougher, Christopher W., Curtin, Leslie, Capitano, Maegan L., Sailsbury-Ruf, Christi T., Repasky, Elizabeth A., Nemeth, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368554/
https://www.ncbi.nlm.nih.gov/pubmed/25793392
http://dx.doi.org/10.1371/journal.pone.0120078