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Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3

Transcription factors are grouped into families based on sequence similarity within functional domains, particularly DNA-binding domains. The Specificity proteins Sp1, Sp2 and Sp3 are paradigmatic of closely related transcription factors. They share amino-terminal glutamine-rich regions and a conser...

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Detalles Bibliográficos
Autores principales: Völkel, Sara, Stielow, Bastian, Finkernagel, Florian, Stiewe, Thorsten, Nist, Andrea, Suske, Guntram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368557/
https://www.ncbi.nlm.nih.gov/pubmed/25793500
http://dx.doi.org/10.1371/journal.pgen.1005102