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Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling

Peptidergic signaling regulates cardiac contractility; thus, identifying molecular switches, ligand-receptor contacts, and antagonists aids in exploring the underlying mechanisms to influence health. Myosuppressin (MS), a decapeptide, diminishes cardiac contractility and gut motility. Myosuppressin...

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Detalles Bibliográficos
Autores principales: Leander, Megan, Bass, Chloe, Marchetti, Kathryn, Maynard, Benjamin F., Wulff, Juan Pedro, Ons, Sheila, Nichols, Ruthann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368603/
https://www.ncbi.nlm.nih.gov/pubmed/25793503
http://dx.doi.org/10.1371/journal.pone.0120492