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Salt Potentiates Methylamine Counteraction System to Offset the Deleterious Effects of Urea on Protein Stability and Function

Cellular methylamines are osmolytes (low molecular weight organic compounds) believed to offset the urea’s harmful effects on the stability and function of proteins in mammalian kidney and marine invertebrates. Although urea and methylamines are found at 2:1 molar ratio in tissues, their opposing ef...

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Detalles Bibliográficos
Autores principales: Rahman, Safikur, Rehman, Md. Tabish, Singh, Laishram R., Warepam, Marina, Ahmad, Faizan, Dar, Tanveer Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368626/
https://www.ncbi.nlm.nih.gov/pubmed/25793733
http://dx.doi.org/10.1371/journal.pone.0119597