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Hepatocyte Nuclear Factor 1A (HNF1A) as a Possible Tumor Suppressor in Pancreatic Cancer

BACKGROUND: HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer. However...

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Detalles Bibliográficos
Autores principales: Luo, Zhaofan, Li, Yanan, Wang, Huamin, Fleming, Jason, Li, Min, Kang, Yaan, Zhang, Ran, Li, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368635/
https://www.ncbi.nlm.nih.gov/pubmed/25793983
http://dx.doi.org/10.1371/journal.pone.0121082