Proteomic Analysis of INS-1 Rat Insulinoma Cells: ER Stress Effects and the Protective Role of Exenatide, a GLP-1 Receptor Agonist

Beta cell death caused by endoplasmic reticulum (ER) stress is a key factor aggravating type 2 diabetes. Exenatide, a glucagon-like peptide (GLP)-1 receptor agonist, prevents beta cell death induced by thapsigargin, a selective inhibitor of ER calcium storage. Here, we report on our proteomic studie...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Kyung, Cho, Jin-Hwan, Lee, Jae-Jin, Son, Moon-Ho, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368701/
https://www.ncbi.nlm.nih.gov/pubmed/25793496
http://dx.doi.org/10.1371/journal.pone.0120536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368701/
https://www.ncbi.nlm.nih.gov/pubmed/25793496
http://dx.doi.org/10.1371/journal.pone.0120536

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