Suppression of TGF-β(1)/Smad Signaling Pathway by Sesamin Contributes to the Attenuation of Myocardial Fibrosis in Spontaneously Hypertensive Rats

This study investigated the effect of sesamin on myocardial fibrosis in spontaneously hypertensive rats (SHRs) and the possible mechanisms involved. Twenty-eight male SHRs were randomly allocated to SHR group, Ses160 group (sesamin 160 mg/kg), Ses80 group (sesamin 80 mg/kg) and Cap30 group (captopri...

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Detalles Bibliográficos
Autores principales: Zhao, Mengqiu, Zheng, Shuguo, Yang, Jieren, Wu, Yuanjie, Ren, Younan, Kong, Xiang, Li, Wei, Xuan, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368740/
https://www.ncbi.nlm.nih.gov/pubmed/25793583
http://dx.doi.org/10.1371/journal.pone.0121312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368740/
https://www.ncbi.nlm.nih.gov/pubmed/25793583
http://dx.doi.org/10.1371/journal.pone.0121312

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