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Protein-Binding RNA Aptamers Affect Molecular Interactions Distantly from Their Binding Sites

Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless,...

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Detalles Bibliográficos
Autores principales: Dupont, Daniel M., Thuesen, Cathrine K., Bøtkjær, Kenneth A., Behrens, Manja A., Dam, Karen, Sørensen, Hans P., Pedersen, Jan S., Ploug, Michael, Jensen, Jan K., Andreasen, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368798/
https://www.ncbi.nlm.nih.gov/pubmed/25793507
http://dx.doi.org/10.1371/journal.pone.0119207