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Protein-Binding RNA Aptamers Affect Molecular Interactions Distantly from Their Binding Sites
Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless,...
Autores principales: | Dupont, Daniel M., Thuesen, Cathrine K., Bøtkjær, Kenneth A., Behrens, Manja A., Dam, Karen, Sørensen, Hans P., Pedersen, Jan S., Ploug, Michael, Jensen, Jan K., Andreasen, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368798/ https://www.ncbi.nlm.nih.gov/pubmed/25793507 http://dx.doi.org/10.1371/journal.pone.0119207 |
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