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The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model

Islet transplantation has become a viable clinical treatment, but is still compromised by long-term graft failure. Exendin-4, a glucagon-like peptide 1 receptor agonist, has in clinical studies been shown to improve insulin secretion in islet transplanted patients. However, little is known about the...

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Detalles Bibliográficos
Autores principales: Sahraoui, Afaf, Winzell, Maria Sörhede, Gorman, Tracy, Smith, Dave M., Skrtic, Stanko, Hoeyem, Merete, Abadpour, Shadab, Johansson, Lars, Korsgren, Olle, Foss, Aksel, Scholz, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368803/
https://www.ncbi.nlm.nih.gov/pubmed/25793295
http://dx.doi.org/10.1371/journal.pone.0121204