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The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term graft failure. Exendin-4, a glucagon-like peptide 1 receptor agonist, has in clinical studies been shown to improve insulin secretion in islet transplanted patients. However, little is known about the...
Autores principales: | Sahraoui, Afaf, Winzell, Maria Sörhede, Gorman, Tracy, Smith, Dave M., Skrtic, Stanko, Hoeyem, Merete, Abadpour, Shadab, Johansson, Lars, Korsgren, Olle, Foss, Aksel, Scholz, Hanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368803/ https://www.ncbi.nlm.nih.gov/pubmed/25793295 http://dx.doi.org/10.1371/journal.pone.0121204 |
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