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Second-Hand Cigarette Smoke Impairs Bacterial Phagocytosis in Macrophages by Modulating CFTR Dependent Lipid-Rafts

INTRODUCTION: First/Second-hand cigarette-smoke (FHS/SHS) exposure weakens immune defenses inducing chronic obstructive pulmonary disease (COPD) but the underlying mechanisms are not fully understood. Hence, we evaluated if SHS induced changes in membrane/lipid-raft (m-/r)-CFTR (cystic fibrosis tran...

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Detalles Bibliográficos
Autores principales: Ni, Inzer, Ji, Changhoon, Vij, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368805/
https://www.ncbi.nlm.nih.gov/pubmed/25794013
http://dx.doi.org/10.1371/journal.pone.0121200