MicroRNA-223 Regulates Granulopoiesis but Is Not Required for HSC Maintenance in Mice

MIR233 is genetically or epigenetically silenced in a subset of acute myeloid leukemia (AML). MIR223 is normally expressed throughout myeloid differentiation and highly expressed in hematopoietic stem cells (HSCs). However, the contribution of MIR223 loss to leukemic transformation and HSC function...

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Detalles Bibliográficos
Autores principales: Trissal, Maria C., DeMoya, Ricardo A., Schmidt, Amy P., Link, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368818/
https://www.ncbi.nlm.nih.gov/pubmed/25793640
http://dx.doi.org/10.1371/journal.pone.0119304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368818/
https://www.ncbi.nlm.nih.gov/pubmed/25793640
http://dx.doi.org/10.1371/journal.pone.0119304

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