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MicroRNA-223 Regulates Granulopoiesis but Is Not Required for HSC Maintenance in Mice
MIR233 is genetically or epigenetically silenced in a subset of acute myeloid leukemia (AML). MIR223 is normally expressed throughout myeloid differentiation and highly expressed in hematopoietic stem cells (HSCs). However, the contribution of MIR223 loss to leukemic transformation and HSC function...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368818/ https://www.ncbi.nlm.nih.gov/pubmed/25793640 http://dx.doi.org/10.1371/journal.pone.0119304 |