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A Single Brain-Derived Neurotrophic Factor Infusion into the Dorsomedial Prefrontal Cortex Attenuates Cocaine Self-Administration-Induced Phosphorylation of Synapsin in the Nucleus Accumbens during Early Withdrawal

BACKGROUND: Dysregulation in the prefrontal cortex-nucleus accumbens pathway has been implicated in cocaine addiction. We have previously demonstrated that one intra-dorsomedial prefrontal cortex brain-derived neurotrophic factor (BDNF) infusion immediately following the last cocaine self-administra...

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Detalles Bibliográficos
Autores principales: Sun, Wei-Lun, Eisenstein, Sarah A., Zelek-Molik, Agnieszka, McGinty, Jacqueline F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368877/
https://www.ncbi.nlm.nih.gov/pubmed/25522393
http://dx.doi.org/10.1093/ijnp/pyu049