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Impaired Limbic Cortico-Striatal Structure and Sustained Visual Attention in a Rodent Model of Schizophrenia

BACKGROUND: N-methyl-d-aspartate receptor (NMDAR) dysfunction is thought to contribute to the pathophysiology of schizophrenia. Accordingly, NMDAR antagonists such as phencyclidine (PCP) are used widely in experimental animals to model cognitive impairment associated with this disorder. However, it...

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Detalles Bibliográficos
Autores principales: Barnes, Samuel A., Sawiak, Stephen J., Caprioli, Daniele, Jupp, Bianca, Buonincontri, Guido, Mar, Adam C., Harte, Michael K., Fletcher, Paul C., Robbins, Trevor W., Neill, Jo C., Dalley, Jeffrey W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368881/
https://www.ncbi.nlm.nih.gov/pubmed/25552430
http://dx.doi.org/10.1093/ijnp/pyu010