Quantification of Central Substance P Receptor Occupancy by Aprepitant Using Small Animal Positron Emission Tomography

BACKGROUND: Central substance P receptors, termed NK-1 receptors, have been considered as therapeutic targets in the development of drugs against diverse conditions, including emesis, overactive bladder, and depression. METHODS: Here, we applied small animal positron emission tomography (PET) and a...

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Detalles Bibliográficos
Autores principales: Endo, Tadashi, Saijo, Takeaki, Haneda, Eisuke, Maeda, Jun, Tokunaga, Masaki, Zhang, Ming-Rong, Kannami, Ayako, Asai, Hidetoshi, Suzuki, Masayuki, Suhara, Tetsuya, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368889/
https://www.ncbi.nlm.nih.gov/pubmed/25609595
http://dx.doi.org/10.1093/ijnp/pyu030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368889/
https://www.ncbi.nlm.nih.gov/pubmed/25609595
http://dx.doi.org/10.1093/ijnp/pyu030

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