Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus

OBJECTIVE: Serine palmitoyltransferase (SPT) catalyzes the condensation of serine and palmitoyl coenzyme A, the first step in the de novo sphingolipid synthesis. Apart from these canonical substrates, SPT can also metabolize alanine and other acyl coenzyme As. This forms a spectrum of atypical sphin...

Descripción completa

Detalles Bibliográficos
Autores principales: Othman, Alaa, Saely, Christoph H, Muendlein, Axel, Vonbank, Alexander, Drexel, Heinz, von Eckardstein, Arnold, Hornemann, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368929/
https://www.ncbi.nlm.nih.gov/pubmed/25815206
http://dx.doi.org/10.1136/bmjdrc-2014-000073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368929/
https://www.ncbi.nlm.nih.gov/pubmed/25815206
http://dx.doi.org/10.1136/bmjdrc-2014-000073

Ejemplares similares