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ViVaMBC: estimating viral sequence variation in complex populations from illumina deep-sequencing data using model-based clustering
BACKGROUND: Deep-sequencing allows for an in-depth characterization of sequence variation in complex populations. However, technology associated errors may impede a powerful assessment of low-frequency mutations. Fortunately, base calls are complemented with quality scores which are derived from a q...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369097/ https://www.ncbi.nlm.nih.gov/pubmed/25887734 http://dx.doi.org/10.1186/s12859-015-0458-7 |