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Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution

BACKGROUND: Long non-coding RNAs (lncRNAs) have been implicated in diverse biological processes. In contrast to extensive genomic annotation of lncRNA transcripts, far fewer have been characterized for subcellular localization and cell-to-cell variability. Addressing this requires systematic, direct...

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Detalles Bibliográficos
Autores principales: Cabili, Moran N, Dunagin, Margaret C, McClanahan, Patrick D, Biaesch, Andrew, Padovan-Merhar, Olivia, Regev, Aviv, Rinn, John L, Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369099/
https://www.ncbi.nlm.nih.gov/pubmed/25630241
http://dx.doi.org/10.1186/s13059-015-0586-4