Cargando…

Variation in longevity gene KLOTHO is associated with greater cortical volumes

OBJECTIVE: Identifying genetic variation associated with brain structures in aging may elucidate new biologic mechanisms underlying resilience to cognitive decline. We investigated whether carrying one copy of the protective haplotype “KL-VS” in longevity gene KLOTHO (KL) is associated with greater...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Jennifer S, Sturm, Virginia E, Bonham, Luke W, Klein, Eric, Arfanakis, Konstantinos, Yu, Lei, Coppola, Giovanni, Kramer, Joel H, Bennett, David A, Miller, Bruce L, Dubal, Dena B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369272/
https://www.ncbi.nlm.nih.gov/pubmed/25815349
http://dx.doi.org/10.1002/acn3.161