Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice

OBJECTIVE: Cellular inclusions of hyperphosphorylated tau are a hallmark of tauopathies, which are neurodegenerative disorders that include Alzheimer's disease (AD). Active and passive immunization against hyperphosphorylated tau has been shown to attenuate phenotypes in model mice. We develope...

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Detalles Bibliográficos
Autores principales: Umeda, Tomohiro, Eguchi, Hiroshi, Kunori, Yuichi, Matsumoto, Yoichi, Taniguchi, Taizo, Mori, Hiroshi, Tomiyama, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369274/
https://www.ncbi.nlm.nih.gov/pubmed/25815351
http://dx.doi.org/10.1002/acn3.171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369274/
https://www.ncbi.nlm.nih.gov/pubmed/25815351
http://dx.doi.org/10.1002/acn3.171

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