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Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice
OBJECTIVE: Cellular inclusions of hyperphosphorylated tau are a hallmark of tauopathies, which are neurodegenerative disorders that include Alzheimer's disease (AD). Active and passive immunization against hyperphosphorylated tau has been shown to attenuate phenotypes in model mice. We develope...
Autores principales: | Umeda, Tomohiro, Eguchi, Hiroshi, Kunori, Yuichi, Matsumoto, Yoichi, Taniguchi, Taizo, Mori, Hiroshi, Tomiyama, Takami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369274/ https://www.ncbi.nlm.nih.gov/pubmed/25815351 http://dx.doi.org/10.1002/acn3.171 |
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