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Drug concentrations in the serum and cerebrospinal fluid of patients treated with cefoperazone/sulbactam after craniotomy

BACKGROUND: To identify changes in cefoperazone/sulbactam penetration into cerebrospinal fluid (CSF) after craniotomy and to investigate preliminarily whether cefoperazone/sulbactam CSF concentration can reach therapeutic level when administered intravenously after neurosurgical operation. METHODS:...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Wu, Yuanxing, Chen, Biyao, Zhou, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369365/
https://www.ncbi.nlm.nih.gov/pubmed/25798070
http://dx.doi.org/10.1186/s12871-015-0012-1