NEDD9/Arf6-Dependent Endocytic Trafficking of Matrix Metalloproteinase 14: A Novel Mechanism for Blocking Mesenchymal Cell Invasion and Metastasis of Breast Cancer

NEDD9 is an established marker of invasive and metastatic cancers. NEDD9 downregulation has been shown to dramatically reduce cell invasion and metastasis in multiple tumors. The mechanisms by which NEDD9 regulates invasion are largely unknown. In the current study, we have found that NEDD9 is requi...

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Detalles Bibliográficos
Autores principales: Loskutov, Yuriy V., Kozyulina, Polina Y., Kozyreva, Varvara K., Ice, Ryan J., Jones, Brandon C., Roston, Trevor J., Smolkin, Matthew B., Ivanov, Alexey V., Wysolmerski, Robert B., Pugacheva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369482/
https://www.ncbi.nlm.nih.gov/pubmed/25241893
http://dx.doi.org/10.1038/onc.2014.297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369482/
https://www.ncbi.nlm.nih.gov/pubmed/25241893
http://dx.doi.org/10.1038/onc.2014.297

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