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Neutralization function affected by single amino acid replacement in the HIV-1 antibody targets

The viral envelope glycoproteins are essential for entry into their host cells and studied extensively for designing vaccines. We hypothesize that the glycosylation on the HIV-1 viral envelope glycoprotein 41(gp41) at critical residues offers viral escape from the specific immune surveillant neutral...

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Detalles Bibliográficos
Autores principales: Christdas, Johnson, Manoharan, Prabu, Harshavardhan, Shakila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369679/
https://www.ncbi.nlm.nih.gov/pubmed/25848164
http://dx.doi.org/10.6026/97320630011057