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Neutralization function affected by single amino acid replacement in the HIV-1 antibody targets
The viral envelope glycoproteins are essential for entry into their host cells and studied extensively for designing vaccines. We hypothesize that the glycosylation on the HIV-1 viral envelope glycoprotein 41(gp41) at critical residues offers viral escape from the specific immune surveillant neutral...
Autores principales: | Christdas, Johnson, Manoharan, Prabu, Harshavardhan, Shakila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369679/ https://www.ncbi.nlm.nih.gov/pubmed/25848164 http://dx.doi.org/10.6026/97320630011057 |
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