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Fibronectin localization and fibrillization are affected by the presence of serum in culture media

In vitro models of fibrotic phenomena are often based on the fibroblast-myofibroblast transition as the contraction-triggering cellular event. There are, however, multiple sources of concern regarding the appropriateness of such models; a first and widely investigated issue is the often inappropriat...

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Detalles Bibliográficos
Autores principales: Siani, Alessandro, Khaw, Rong R., Manley, Oliver W. G., Tirella, Annalisa, Cellesi, Francesco, Donno, Roberto, Tirelli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369722/
https://www.ncbi.nlm.nih.gov/pubmed/25797118
http://dx.doi.org/10.1038/srep09278