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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids

Flavonoids were found previously to modulate efficiency of synthesis of glycosaminoglycans (GAGs), compounds which are accumulated in cells of patients suffering from mucopolysaccharidoses (MPSs). The aim of this work was to determine effects of different flavonoids (genistein, kaempferol, daidzein)...

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Detalles Bibliográficos
Autores principales: Moskot, Marta, Jakóbkiewicz-Banecka, Joanna, Kloska, Anna, Smolińska, Elwira, Mozolewski, Paweł, Malinowska, Marcelina, Rychłowski, Michał, Banecki, Bogdan, Węgrzyn, Grzegorz, Gabig-Cimińska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369724/
https://www.ncbi.nlm.nih.gov/pubmed/25797591
http://dx.doi.org/10.1038/srep09378