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Poly (I:C) therapy decreases cerebral ischaemia/reperfusion injury viaTLR3-mediated prevention of Fas/FADD interaction

Toll-like receptor (TLR)-mediated signalling plays a role in cerebral ischaemia/reperfusion (I/R) injury. Modulation of TLRs has been reported to protect against cerebral I/R injury. This study examined whether modulation of TLR3 with poly (I:C) will induce protection against cerebral I/R injury. Mi...

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Detalles Bibliográficos
Autores principales: Zhang, Xia, Ha, Tuanzhu, Lu, Chen, Lam, Fred, Liu, Li, Schweitzer, John, Kalbfleisch, John, Kao, Race L, Williams, David L, Li, Chuanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369813/
https://www.ncbi.nlm.nih.gov/pubmed/25351293
http://dx.doi.org/10.1111/jcmm.12456