Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection

Di(2-ethylhexyl) phthalate (DEHP) is used as plasticizer and is ubiquitously found in the environment. Exposure to DEHP has been linked to an increased incidence of type 2 diabetes. Pancreatic β-cell dysfunction is a hallmark of type 2 diabetes; however, it is unknown whether DEHP exposure contribut...

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Detalles Bibliográficos
Autores principales: Sun, Xia, Lin, Yi, Huang, Qiansheng, Shi, Junpeng, Qiu, Ling, Kang, Mei, Chen, Yajie, Fang, Chao, Ye, Ting, Dong, Sijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369815/
https://www.ncbi.nlm.nih.gov/pubmed/25418486
http://dx.doi.org/10.1111/jcmm.12409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369815/
https://www.ncbi.nlm.nih.gov/pubmed/25418486
http://dx.doi.org/10.1111/jcmm.12409

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