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A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) play an important role in breast cancer pathogenesis by paracrine regulation of breast cancer cell biology. Several in vitro and mouse models have characterized the role of cell contact and cytokine molecules mediating this relationship, although few...

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Detalles Bibliográficos
Autores principales: Hosein, Abdel Nasser, Livingstone, Julie, Buchanan, Marguerite, Reid, James F, Hallett, Michael, Basik, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369836/
https://www.ncbi.nlm.nih.gov/pubmed/25884794
http://dx.doi.org/10.1186/s12885-015-1117-0