Cargando…

A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) play an important role in breast cancer pathogenesis by paracrine regulation of breast cancer cell biology. Several in vitro and mouse models have characterized the role of cell contact and cytokine molecules mediating this relationship, although few...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hosein, Abdel Nasser, Livingstone, Julie, Buchanan, Marguerite, Reid, James F, Hallett, Michael, Basik, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369836/ https://www.ncbi.nlm.nih.gov/pubmed/25884794 http://dx.doi.org/10.1186/s12885-015-1117-0

Ejemplares similares

The crosstalk between breast carcinoma-associated fibroblasts and cancer cells promotes RhoA-dependent invasion via IGF-1 and PAI-1
por: Daubriac, Julien, et al.
Publicado: (2017)

A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro
por: Gattas, María José, et al.
Publicado: (2021)

Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer
por: Buess, Martin, et al.
Publicado: (2007)

Tumor cell-fibroblast heterotypic aggregates in malignant ascites of patients with ovarian cancer
por: Han, Qing, et al.
Publicado: (2019)

Heterotypic signaling of cancer-associated fibroblasts in shaping the cancer cell drug resistance
por: Butti, Ramesh, et al.
Publicado: (2023)

Heterotypic Supramolecular Hydrogels Formed by Noncovalent Interactions in Inflammasomes
por: Shy, Adrianna N., et al.
Publicado: (2020)

Cellular Plasticity and Heterotypic Interactions during Breast Morphogenesis and Cancer Initiation
por: Ingthorsson, Saevar, et al.
Publicado: (2022)

Cadherin-23 Mediates Heterotypic Cell-Cell Adhesion between Breast Cancer Epithelial Cells and Fibroblasts
por: Apostolopoulou, Maria, et al.
Publicado: (2012)

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung
por: Lugo, Roberto, et al.
Publicado: (2016)

Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures
por: Tan, Justin J. Y., et al.
Publicado: (2019)

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions
por: Farag, Mina, et al.
Publicado: (2023)

Involvement of the Lamin Rod Domain in Heterotypic Lamin Interactions Important for Nuclear Organization
por: Schirmer, Eric C., et al.
Publicado: (2001)

HETEROTYPIC INTERACTIONS ENABLED BY POLARIZED NEUTROPHIL MICRODOMAINS MEDIATE THROMBO-INFLAMMATORY INJURY
por: Hidalgo, Andrés, et al.
Publicado: (2009)

Heterotypic Cellular Interactions in the Ovarian Tumor Microenvironment: Biological Significance and Therapeutic Implications
por: Naora, Honami
Publicado: (2014)

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate
por: Ragotte, Robert J., et al.
Publicado: (2022)

Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers
por: Louros, Nikolaos, et al.
Publicado: (2022)

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association
por: Patel, Onisha, et al.
Publicado: (2017)

Heterotypic Stressors Unmask Behavioral Influences of PMAT Deficiency in Mice
por: Weber, Brady L., et al.
Publicado: (2023)

Heterotypic stressors unmask behavioral influences of PMAT deficiency in mice
por: Weber, Brady L, et al.
Publicado: (2023)

Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish
por: Mahalwar, Prateek, et al.
Publicado: (2016)

Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein
por: Dhakal, Shailendra, et al.
Publicado: (2022)

Prevalence of Heterotypic Tumor/Immune Cell-In-Cell Structure In Vitro and In Vivo Leading to Formation of Aneuploidy
por: Chen, Yu-hui, et al.
Publicado: (2013)

Cooperativity-based modeling of heterotypic DNA nanostructure assembly
por: Shapiro, Anastasia, et al.
Publicado: (2015)

Heterotypic and homotypic continuity in psychopathology: a narrative review
por: Speranza, Anna Maria, et al.
Publicado: (2023)

Heterotypic tumor spheroids: a platform for nanomedicine evaluation
por: Vakhshiteh, Faezeh, et al.
Publicado: (2023)

Modelling breast cancer in a three-dimensional heterotypic culture system
por: Holliday, DL, et al.
Publicado: (2010)

Macrophage Plasticity and Function in the Lung Tumour Microenvironment Revealed in 3D Heterotypic Spheroid and Explant Models
por: Evans, Lauren, et al.
Publicado: (2021)

Micropatterned co-culture of hepatocyte spheroids layered on non-parenchymal cells to understand heterotypic cellular interactions
por: Otsuka, Hidenori, et al.
Publicado: (2013)

Studying Heterotypic Cell–Cell Interactions in the Human Brain Using Pluripotent Stem Cell Models for Neurodegeneration
por: Song, Liqing, et al.
Publicado: (2019)

Differential homotypic and heterotypic interactions of antigen 43 (Ag43) variants in autotransporter-mediated bacterial autoaggregation
por: Ageorges, Valentin, et al.
Publicado: (2019)

Phase Separation in Mixtures of Prion-Like Low Complexity Domains is Driven by the Interplay of Homotypic and Heterotypic Interactions
por: Pappu, Rohit, et al.
Publicado: (2023)

Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates
por: Rai, Sandeep K., et al.
Publicado: (2023)

Spatial self-organization favors heterotypic cooperation over cheating
por: Momeni, Babak, et al.
Publicado: (2013)

Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies
por: Chuang, Katherine, et al.
Publicado: (2015)

Homotypic and heterotypic psychopathological continuity: a child cohort study
por: Shevlin, Mark, et al.
Publicado: (2017)

Complex Scenario of Homotypic and Heterotypic Zika Virus Immune Enhancement
por: Marques, Ernesto T. A., et al.
Publicado: (2019)

Sorting at embryonic boundaries requires high heterotypic interfacial tension
por: Canty, Laura, et al.
Publicado: (2017)

Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly
por: Balaji, Vishnu, et al.
Publicado: (2020)

Heterotypic Multicellular Spheroids as Experimental and Preclinical Models of Sprouting Angiogenesis
por: Vakhrushev, Igor V., et al.
Publicado: (2021)

The solubility product extends the buffering concept to heterotypic biomolecular condensates
por: Chattaraj, Aniruddha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_apj3r1iee0merhi76eo60ah11r