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Neural stem and progenitor cell fate transition requires regulation of Musashi1 function

BACKGROUND: There is increasing evidence of a pivotal role for regulated mRNA translation in control of developmental cell fate transitions. Physiological and pathological stem and progenitor cell self-renewal is maintained by the mRNA-binding protein, Musashi1 through repression of translation of k...

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Detalles Bibliográficos
Autores principales: MacNicol, Angus M, Hardy, Linda L, Spencer, Horace J, MacNicol, Melanie C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369890/
https://www.ncbi.nlm.nih.gov/pubmed/25888190
http://dx.doi.org/10.1186/s12861-015-0064-y