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Shengmai Injection Improved Doxorubicin-Induced Cardiomyopathy by Alleviating Myocardial Endoplasmic Reticulum Stress and Caspase-12 Dependent Apoptosis

Background. Apoptosis plays vital roles in the progression of doxorubicin-induced cardiomyopathy (DOX-CM). Endoplasmic reticulum stress (ER stress) could induce specific apoptosis by caspase-12 dependent pathway. Shengmai Injection (SMI), a famous Traditional Chinese Medicine, could alleviate the he...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Tang, Yong, Xiang, Yin, Xie, Yu-Quan, Huang, Xiao-Hong, Zhang, Ya-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369903/
https://www.ncbi.nlm.nih.gov/pubmed/25839043
http://dx.doi.org/10.1155/2015/952671