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A Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive Animals

Interleukin (IL)-17 plays a key role in immunity. In acute infections, a rapid IL-17 response must be induced without prior antigen exposure, and γδ T cells are the major initial IL-17 producers. In fact, some γδ T cells make IL-17 within hours after an immune challenge. These cells appear to acquir...

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Detalles Bibliográficos
Autores principales: Wei, Yu-Ling, Han, Arnold, Glanville, Jacob, Fang, Fengqin, Zuniga, Luis Alejandro, Lee, Jacob S., Cua, Daniel J., Chien, Yueh-hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370043/
https://www.ncbi.nlm.nih.gov/pubmed/25852688
http://dx.doi.org/10.3389/fimmu.2015.00118