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Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus

Enhancers are closely positioned with actively transcribed target genes by chromatin looping. Non-coding RNAs are often transcribed on active enhancers, referred to as eRNAs (enhancer RNAs). To explore the kinetics of enhancer–promoter looping and eRNA transcription during transcriptional activation...

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Detalles Bibliográficos
Autores principales: Kim, Yea Woon, Lee, Sungkung, Yun, Jangmi, Kim, AeRi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370096/
https://www.ncbi.nlm.nih.gov/pubmed/25588787
http://dx.doi.org/10.1042/BSR20140126