Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness

Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival. Clinical trials have shown that doxycycline treatment eliminates Wolbachia, causing long-term sterilization...

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Detalles Bibliográficos
Autores principales: Walker, Martin, Specht, Sabine, Churcher, Thomas S., Hoerauf, Achim, Taylor, Mark J., Basáñez, María-Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles and Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370165/
https://www.ncbi.nlm.nih.gov/pubmed/25537873
http://dx.doi.org/10.1093/cid/ciu1152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370165/
https://www.ncbi.nlm.nih.gov/pubmed/25537873
http://dx.doi.org/10.1093/cid/ciu1152

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