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Generation of three dimensional retinal tissue with functional photoreceptors from human iPSCs

Many forms of blindness result from the dysfunction or loss of retinal photoreceptors. Induced pluripotent stem cells (iPSC) hold great potential for the modeling of these diseases or as potential therapeutic agents. However, to fulfill this promise, a remaining challenge is to induce human iPSC to...

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Detalles Bibliográficos
Autores principales: Zhong, Xiufeng, Gutierrez, Christian, Xue, Tian, Hampton, Christopher, Vergara, M. Natalia, Cao, Li-Hui, Peters, Ann, Park, Tea-Soon, Zambidis, Elias T., Meyer, Jason S., Gamm, David M., Yau, King-Wai, Canto-Soler, M. Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370190/
https://www.ncbi.nlm.nih.gov/pubmed/24915161
http://dx.doi.org/10.1038/ncomms5047