Cargando…

Flavone Derivatives as Inhibitors of Insulin Amyloid-Like Fibril Formation

Several natural and synthetic flavone derivatives have been reported to inhibit formation of amyloid fibrils or to remodel existing fibrils. These studies suggest that the numbers and positions of hydroxyl groups on the flavone rings determine their effectiveness as amyloid inhibitors. In many studi...

Descripción completa

Detalles Bibliográficos
Autores principales: Malisauskas, Ricardas, Botyriute, Akvile, Cannon, Jonathan G., Smirnovas, Vytautas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370379/
https://www.ncbi.nlm.nih.gov/pubmed/25799281
http://dx.doi.org/10.1371/journal.pone.0121231