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Flavone Derivatives as Inhibitors of Insulin Amyloid-Like Fibril Formation
Several natural and synthetic flavone derivatives have been reported to inhibit formation of amyloid fibrils or to remodel existing fibrils. These studies suggest that the numbers and positions of hydroxyl groups on the flavone rings determine their effectiveness as amyloid inhibitors. In many studi...
Autores principales: | Malisauskas, Ricardas, Botyriute, Akvile, Cannon, Jonathan G., Smirnovas, Vytautas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370379/ https://www.ncbi.nlm.nih.gov/pubmed/25799281 http://dx.doi.org/10.1371/journal.pone.0121231 |
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